Nanobiology Research Services & Instruments

SEM butterfly wing

SEM image of a butterfly wing, showing two overlapping scales and banded elements that create the structural color of the wing

M13 dsDNA from cold storage

Correctly stored aliquot of M13 dsDNA with various degrees of supercoiling

TEM kidney GBM

TEM image of a thin section through the glomerular basement membrane and a podocyte cell in mouse kidney

circular DNA aggregates imaged with an HR-AFM

DNA ladder measurements

Segmented length measurements of a DNA ladder from 50 to 1,350 base pairs.

PrP amyloid 2x2um visualization

AFM visualization of recombinant major prion protein (PrP) amyloid formation

polycarbonate filtration membrane 1.5 um pore size

AFM topography image of polycarbonate membrane with a specified 1.5 um pore size

collagen network in eggs

Collagen I network in the eggshell membrane

bacterial colony picked off an agar plate

skin microbiome epithelial cell with cocci

two-component hydrogel, topography

polycarbonate filtration membrane pores with line profiles, specified 0.8 um

bacterial biofilm with bacterial cell surfaces and fimbriae, 3d rendered

Topography of polymer substrate wiped with ethanol

Wiping a polymer substrate with ethanol removed most particulates but scratched the surface.

single-molecule ssDNA measurements

Measuring and visualizing individual M13 ssDNA molecules

DNA on mica terraces imaged with an HR-AFM

M13 dsDNA after RT storage

Fragmented M13 dsDNA after extended storage at room temperature

SEM housefly head

SEM image of a housefly head showing compound eyes, sensory hairs and olfactory organs

oral microbiome epithelial cell from a cheek swab with bacilli

M13 ssDNA, 1×1 um scan

cheek cell in 3D, rendered and shadowed

3D rendering of an epithelial cell from a cheek swab highlighting surface ruffles and the oral microbiome (red bacteria)

Bacterial Biofilm 3D visualization

bacterial biofilm in the AFM showing bacterial cells encased by fimbriae (extracellular matrix)

correlative microscopy, AFM topography scan of epithelial cell, 3d rendered

bacterial biofilm with bacterial surfaces and fimbriae, phase

bacterial colony from an agar plate

Nanoscale arrangement of cellulose fibers in a protein dialysis membrane

AFM reveals the arrangement of cellulose nanofibers in a dialysis membrane

collagen I network in the eggshell membrane, topography

Medical device biofilm

A bacterial biofilm found in a CPAP machine with bacterial cells (ruffled surfaces) emanating from the surrounding extracellular matrix

skin microbiome – epithelial cell with cocci and bacilli, 3d rendered

PrP amyloid 5x5um topography

AFM image of recombinant major prion protein (PrP) with color-indexed height.

Polycarbonate filtration membrane

Pore distribution in a polycarbonate filtration membrane

AFM of Gram stained cheek cell

AFM topography image of a Gram stained epithelial cell

1×1 um scan circular DNA imaged with an HR-AFM showing fragmentation of the DNA

fimbriae in a bacterial biofilm, 3d rendered

Tap water before filtration

AFM topography image of microparticles in unfiltered tap water

PrP automated segmentation labeled

Automated segmentation and labeling of a PrP amyloid sample for comparison of single-segment measurements.

biofilm in a rain puddle

AFM image of an environmental biofilm with a pollen, a large protist and numerous bacterial cells

polymer substrate before cleaning cropped area

AFM topography image of a polymer substrate right after removing the protective film

polymer substrate before cleaning, topography

AFM topography image of a polymer substrate right after removing the protective film

fork in genomic DNA with line profiles

filtered water phase

AFM phase image of microparticles in tap water that was filtered through a pitcher filter

AAV particle topography

AFM image of Adeno-associated virus (AAV) capsids with color-indexed height

red blood cells rendered in 3D

red blood cells embedded in coagulated blood proteins rendered in 3D

cellulose dialysis membrane overview

plain printer paper with embedded cellulose fibers

coagulated red blood cells, topography

flagellum in a biofilm

A flagellum emanating from a protist cell that was observed in an environmental biofilm (rain puddle)

oral microbiome epithelial cell from a cheek swab with bacilli and cocci, topography

SEM ladybug leg

SEM image of a ladybug leg with claws and foot pads

polymer substrate before cleaning, phase

AFM phase image of a polymer substrate right after removing the protective film

casein micelles in milk on polycarbonate membrane

High resolution scan showing casein micelles in milk after filtration through a polycarbonate membrane

correlative microscopy, AFM topography scan of epithelial cell

M13 dsDNA visualization

Visualization of M13 dsDNA showing various degrees of supercoiling and minor fragmentation

two-component hydrogel, phase image

phase image of a two component hydrogel showing regions with different stiffness

bacterial colony in 3D

Quality control of a bacterial colony picked directly from an agar plate

filtered water topography

AFM topography image of microparticles in tap water that was filtered through a pitcher filter

egg white proteins, topography

oral microbiome epithelial cell from cheek swab with bacteria

polymer substrate, ethanol rinsed, topography

denatured collagen network in the eggshell membrane of a hardboiled egg, topography

PES filtration membrane

AFM topography image of a polyether sulfone membrane with a specified 0.22 um pore size

M13amp18 ssDNA, 4×4 um

Overview scan of ssDNA molecules for quality control

PrP maximum height histogram

Automated extraction and graphing of maximum height of a PrP amyloid sample

AAV maximum height histogram

Maximum height distribution of AAV particles, extracted automatically from AFM data

fimbriae in a bacterial biofilm, topography