Specialized Applications

“The most exciting phrase to hear in science, the one that heralds new discoveries, is not ‘Eureka!’ but ‘That’s funny…’“- Isaac Asimov

We understand how difficult it is to access nanoscale imaging capabilities. It shouldn’t be! BioCubic is here to support you, step by step.

AFM can be used to measure and visualize so many types of biomaterials for specialized applications that it’s hard to keep track of. See below for some common and less common examples! If your material of interest isn’t here, don’t hesitate to reach out through our contact form.

  • AFM image of a bacterial biofilm with fimbriae, rendered and shadowed
    AFM vs. TEM and SEM

    How do AFMs compare with TEM and SEM in life sciences? These three microscope technologies deliver complementary information, with AFM being unique in its ability to deliver quantitative 3D and nanomechanical data in liquids.

    1.9 min read
  • atomic force microscopy topography scan of epithelial cell from a cheek swab
    Correlative imaging of cells with the LS-AFM

    When mounted on an inverted light microscope, AFMs deliver powerful correlative microscopy data on cells and subcellular features.

    3.8 min read
  • collagen I network in eggshell membrane at the air pocket
    How the AFM teaches serendipity using eggshells!

    Why we need to teach serendipity in education and research and how an AFM can help!

    5.6 min read
  • single-stranded DNA from bacteriophage M13 imaged by AFM
    Imaging DNA with the HR-AFM

    AFMs are the most efficient tool to measure DNA for research and quality control applications. Our expertise allows us to consistently prepare and image single- and double-stranded DNA constructs.

    3.9 min read
  • AFM phase image of a polymer substrate before cleaning, revealing a difference in stiffness of a droplet contamination
    Phase imaging with the AFM

    AFM is the only nanocharacterization method that delivers mechanical information about the sample surface. Phase imaging is the most straightforward mode to access mechanical data in biomaterials.

    4 min read
  • red blood cells embedded in coagulated blood, rendered in 3D
    What makes AFM so special?

    AFM is the simplest, most affordable imaging tool for education, research and quality control at the nanoscale. Why aren't we using it more?

    3.6 min read